Phase 0 Clinical Trials

Phase 0 Clinical Trials is a type of clinical trial that is used in medical research as the first type of human trials. These trials come right after the preclinical trial stage and are used in order to diagnose early on whether a certain type of drug or treatment is safe and beneficial to a human participant. These type of trials are conducted using regulations that the FDA have set up for studies such as these and they are also known as microdosing studies because they involve the administering of below therapeutic doses of a certain medication for testing. The features of this type of clinical trial also include using it for diagnosing exactly how a certain drug effects the body and also what the body does to a drug once it enters in.

The phase 0 clinical trials help researchers to find out many aspects of the interaction of a drug in the human body but what it is not used for is giving information about the safety of a drug. This is because the drug dosage that is used in a phase 0 clinical trial is too low to be of any therapeutic use. This type of clinical trial is also used by drug companies that develop medication in order to decide what drugs are the best to put on the market and further develop. This also gives a drug company more information on a drugs effect on humans as opposed to simply using animal studies to suggest what effects may be had by a particular drug. With all of the information that is gathered through this type of trial it is not hard to tell why researchers use them so often at the primary stages of the whole clinical trial process.